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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
26.67
Human Site:
Y112
Identified Species:
53.33
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
Y112
D
Y
A
S
N
C
L
Y
M
E
E
I
E
G
S
Chimpanzee
Pan troglodytes
XP_514697
253
28128
Y112
D
Y
A
S
N
C
L
Y
M
E
E
I
E
G
S
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
T77
V
R
D
Y
I
Q
S
T
M
E
T
E
K
T
P
Dog
Lupus familis
XP_853966
302
33650
Y161
D
Y
A
S
N
C
L
Y
M
E
E
I
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
Y103
D
Y
A
S
N
C
L
Y
M
E
E
I
E
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
Y173
D
Y
A
S
N
C
I
Y
L
E
D
I
V
G
A
Frog
Xenopus laevis
NP_001089506
237
26742
Y96
D
Y
V
S
N
C
I
Y
L
E
D
I
E
E
S
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
F94
D
Y
A
T
H
C
I
F
L
Q
D
V
V
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
A89
Y
F
D
A
A
K
T
A
K
Q
F
I
Q
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
T88
D
P
L
L
H
A
L
T
F
E
Y
V
E
G
P
Maize
Zea mays
NP_001146448
226
25230
T88
D
P
V
L
H
T
L
T
F
E
H
V
D
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
D112
W
L
E
F
L
G
E
D
L
P
G
G
H
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
93.3
N.A.
N.A.
N.A.
66.6
66.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
86.6
86.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
33.3
26.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
46.6
46.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
9
9
9
0
9
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
17
0
0
0
0
9
0
0
25
0
9
9
0
% D
% Glu:
0
0
9
0
0
0
9
0
0
75
34
9
50
17
0
% E
% Phe:
0
9
0
9
0
0
0
9
17
0
9
0
0
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
9
9
0
59
0
% G
% His:
0
0
0
0
25
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
25
0
0
0
0
59
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% K
% Leu:
0
9
9
17
9
0
50
0
34
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
9
0
0
0
17
0
0
9
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
50
0
0
9
0
0
0
0
0
0
0
50
% S
% Thr:
0
0
0
9
0
9
9
25
0
0
9
0
0
9
9
% T
% Val:
9
0
17
0
0
0
0
0
0
0
0
25
17
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
59
0
9
0
0
0
50
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _